Ozempic Side Effects

so first from Wellness Resources we're going to talk about OIC and this is OIC side effects include pancreatitis stomach paralysis and thyroid cancer now before we dive into the article I'm going to play a clip because it's one thing to talk about the article and kind of go through it but I want you to see what's out there in the news and I want you to see exactly how people are talking about it and um you know because it's again it's all the rage it's it's mainstream and all this so take a look at what they're talking about when it comes to OIC and these types of uh you know weight loss drugs and what they call they're kind of like you know Miracle weight loss drugs or whatever the case may be and um and you know for those of you who are listening you know you'll be able to kind of understand what's going on but um check this out so you can kind of get a sense of what's going on out there these days it's the talk of Tik Tok I just start dropping pounds left and right the topic OIC has over 300 million views being on this medication has helped me tremendously with my health with scores of users crediting the drug for their weight loss success OIC is a drug you inject that's meant to improve blood sugar and help manage type 2 diabetes but because one of the side effects is weight loss many are using it off label a trend that may have started in Hollywood talk show host Andy Cohen even recently tweeting everyone is suddenly showing up 25 lbs lighter what happens when they stop taking OIC since oic's gone viral on social media some doctors like Nancy Rama say they've been flooded with inquiries it's become something very hot and heavy in Los Angeles Beverly Hills oic's active ingredient seatide works by making you feel full longer doctors say it's similar to wovi which has been approved for weight loss by the FDA and is produced by the same manufacturer Novo Nordisk when we ask the company about people using OIC to lose weight it responded in a statement writing in part we do not promote suggest or encourage off-label use of our medicines the company adding OIC and wovi are not interchangeable however the FDA tells NBC News healthc Care Professionals can choose to prescribe drugs off label when medically appropriate Anna M has documented her 45lb weight loss Journey with OIC on YouTube interestingly enough it has been my easiest weight loss attempt and my most successful she agrees that OIC isn't a magic pill adding her side effects have included headaches and fatigue a price some may be willing to pay for weight loss and that's the issue right the the the price that some are willing to pay for weight loss that's really the issue and part of the reason why this whole culture exists is well there's a I mean there's a many reasons for it but of course you know they're marketing a drug they're marketing something they can sell makes sense but there's also Public Health officials out there who are saying things you know on TV and and this type of thing who kind of add to this and people see this and then they think well yeah that makes sense right so take a look at this and I I I played this once before but let's see if you remember these comments if you diet you lose weight right the number one cause of obesity is genetics that means if you are born to parents that have obesity you have a 50 to 85% likelihood of having the disease yourself even with optimal diet exercise sleep management Stress Management so when people see families that have obesity the assumption is what are they feeding those kids and that's part of the reason why this is the message that our health officials out there our our Public Health officials and our scientists and this is what they're this is what they're selling this is what they're talking about okay and this is part of the reason why people are getting this message and then running every time they see something you know shiny and new without thinking about the consequence now again that's it is what it is now that was Dr Fatima Cody right who is a person who who's you know pretty high as far as public health she's a Stanford Graduate she's a scientist and she's basically a um an obesity expert and I that was a clip from 60 minutes if I remember correctly and that is but this is what it is this is what they're actually promoting this is basically what they're saying is don't worry about it it's a disease it's not your fault diet and exercise have nothing to do with it if you're o obese don't worry we can fix that we have something for you and it's sad it's sad because people buy into this and then this is those are the folks that run and get you know the oics and and and all these types of things and um and then who knows where they end up with it whether it's side effects or not but they see the weight dropping pretty quick and um and there you go so this is what's going on out there you know so obviously you know everybody got has to be aware of this stuff so let's let's dive into OIC and these types of drugs directly from the article okay so OIC basically is a once- a week injection approved by the FDA in 2017 and it was it was approved initially to treat type two diabetes okay and it's not currently just and again it's not currently approved by the FDA for weight loss it's a side effect it's a side effect that's what's interesting right it's the side effect is weight loss okay so again oic's main ingredient is seatide right or some people say semaglutide okay but what it does is it activates What's called the glp1 receptor now the idea for The gp1 Agonist uh Agonist drugs which which this is stems from a it was a Canadian researcher in 1984 that was studying uh these these was studying the the use of lizard Venom actually from the what's called a key monster okay it's like kind of like a big giant lizard and this reptile basically can slow down it its metabolism and sustain blood sugar levels due to a hormone called extendin four okay so basically what this did is it spurred This research to develop a drug that kind of mirrors what that does in this this lizard and that's kind of how that started now the prescriptions for OIC and similar DRS have skyrocketed to 9 million in 2023 9 million so that's that's a lot okay so let's talk about glp1 first because it is a hormone okay and let's talk about exactly what the hormone does now glp just so you know it stands for gluc glucagon like peptide okay and it was basically discovered when they were looking at uh you know these receptors in the pancreas and these different hormones in the pancreas and they were they were discovering what it does and they they kind of discovered this glp1 and exactly how it affects and and acts similar to glucagon now we know glucagon in your system if you know anything about how that works glucagon is kind of the companion hormone to insulin basically insulin what is insulin do right so when you take in Sugar insulin is secreted by your pancreas and basically takes the sugar out of your bloodstream right and kind of puts it on kind of as a carrier and basically distribut it to where it needs to go it goes into your cells it goes into your muscular Skittle system it goes into your brain it gets put into the fat if has nowhere else to go that type of thing so you know insulin is kind of like the taxi cab driving around the passengers okay so you know that's what it does okay now glucagon is a little bit of has a little bit of a different mechanism because when your blood sugar goes down and we're talking about when you start when you start to experience a little more of a hypoglycemia meaning your blood sugar goes way down and you'll notice let's say you haven't eaten in a long time you you're more sensitive you your blood sugar goes way down you start getting laded you start feeling woozy right your blood sugar go that means that your blood sugar's you know going down well typically what glucagon is supposed to do is supposed to get secreted between your meal or between those times go into your liver knock on the door of your liver basically and tell your liver to release the stored blood sugar that that's called glycogen in there and release it turn it into glucose and basically keep your head awake okay and historically that's what it does right that's typically how it's Works since the an Our Ancestors right because remember our ancestor has our ancestors had to keep their head awake because they didn't get three or four square meals a day so the body Evol you know through Evolution has worked that way right well now we we're so metabolically unhealthy in society that all these hormones are completely out of whack and this is where we start to get problems this is where we start to get obesity problems hypoglycemia hyperglycemia diabetes all these types of things because we are just metabolically inflexible okay so and again that's just kind of a little bit of the backstory but let's talk about gp1 hormone so in humans the gp1 is a natural hormone produced and secreted by the Endocrine cells in your small intestine okay and one of the things it does it basically enters your brain upon eating food okay and it has several functions in uh in the body okay it causes your pancreas to release insulin okay that's one it's a good thing it does it blocks glucagon okay it actually blocks glucagon when when that raise you know which is again what raises the uh blood sugars when your when the your blood sugar runs low so it blocks glucagon now okay keep that in mind okay now glp1 also slows the gastric emptying causing slower digestion and this is the big one this is the big one because it actually slow it causes a slowing down of the digestive process and why is that important because of satiety because remember it takes you what 15 to 20 minutes to feel the full signal when you're eating well if you are eating slow if you if you have a slow slower effect of gastric emptying into the digestive system okay you're going to start to feel a little more Sati you're going to start to feel full uh for a longer period of time digestion is going to slow now this is something that I've talked about that you know fiber helps to do as well okay but also the gp1 signals areas in your brain that process hunger and satiety so this is what gp1 does in your in your body just normally as a as a normal hormone okay now the differences is the gp1 naturally produced in your body has a half life of about one to two minutes okay so it and it stays in your system for about 5 minutes now each injection of synthetic glp1 okay CU remember this is what this is what these oics and these types of things are right they're injections these injections of the glp1 semaglutide stays in your system for five weeks what could possibly go wrong five weeks okay so this is why you're starting to get weight loss right you start to get weight loss why because basically when you look when you drill down to it and the mechanism is is that you're feeling full longer you're feeling you're not eating as much right and therefore you're starting to get you're starting to get weight loss okay this is this is part of that whole mechanism and this was again this was a side effect of using these drugs for diabetics because what these what these drugs do really was were designed to control your diabetes right we're to control your insulin levels and these type of things which is not a bad thing but the issue is now where actually causing the body to lose weight now is that a good or a bad thing we'll talk about that but let's move on now wovi which which was is a more potent version of OIC okay and that was designed for weight loss and that was actually that was actually introduced nfda proofed for weight loss okay and that was in 2021 way GOI isn't approved for individuals with a body mass index of at least 30 it it is also approved for use in individuals with a BMI of at least 27 and a medical condition uh related to weight uh you know related to weight like cholesterol diabetes and high blood pressure the FDA just approved wovi as the first weight loss medication to help prevent heart heart stroke and cardiovascular events in adults with cardiovascular disease and other obesity or overweight issues okay so they're all in on wovi so we'll move on so let's talk a little bit about why this could be a problem okay and I'm going to address it first and it's not from this article but I'm going to address something that this article actually doesn't mention but what people are seeing in um and what studies are seeing in these people that have lost weight on these medications when they've looked at dexa scans from a lot of these people who have lost weight on these drugs yes they've lost weight but they're also losing money muscle at the same rate that's a problem that's a problem because we all know right muscle mass and muscle loss as you get older sarcopenia is a major problem because now you are leading to metabolic problems if you are losing muscle as you get older that's causing a whole range of problems because that's going to make you more susceptible overall to insulin resistance in general but it's also going to make you susceptible to a lot of other things including including falling balance issues breaking you know breaking bones and these types things things that you don't want to happen as you get older as you become you know uh especially after 60s and 70s and that type of thing so the more muscle mass you have into your older ages the better off you are going to be metabolically flexible and I've talked about it a lot on this show you must maintain your muscle mass as you get older and it's even more imperative that as you lose weight if you are obese or just overweight that you maintain that muscle mass as you lose weight because again you can lose them both and what they're seeing in the dexas scans is that people are losing both that's a problem okay so that's just my research on this as well again they're going to do more studies on this but I have a feeling that this is part of the problem so now let's go you know let's dive a little bit deeper into the um side effects okay of these things so pancreatitis diabetic retinopathy kidney disease okay so some of the FDA warnings and precautions include pancreatitis which is inflammation of the pancreas right okay diabetic retinopathy complications Vision vision changes due to blindness severe hypoglycemia acute kidney injury and worsening of you know chronic kidney disease which may require Dialysis in some cases and acute gallbladder disease also they've noticed sweating confusion uh drowsiness headaches slurge speech fast heartbeat anxiety irritability mood changes weakness and feeling jittery okay again things to keep in the back of your mind when it comes to this these are all warnings by the way also thyroid cancer warnings OIC or semaglutide also carries a boxed warning that it may cause thyroid cancer animal studies showed that OIC caused increased incident of meary thyroid cancer that has not been proven in humans so again this is animal studies so obviously you know you have to take that for what it is but it's something to take a look at because a lot of animal studies that they do they make sure that the animals are as you know as close to humans as possible Right their their environment and and that type of thing so I'm sure eventually hope they'll do some more studies on humans on this next stomach paralysis and intestinal blockages so in SE September 2023 the FDA added a warning for intestinal blockage intestinal obstruction and ilas uh where the intestine stopped working properly and I talked about this on a previous podcast this was one of the big things that came out especially there were people a lot of people in Europe who were taking this that were experiencing that and I think that's where it started actually that's where the first the first complaints were happening I think it was somewhere in Europe I don't remember exactly where but anyway in 2023 October the American Medical Association uh published a research letter on the further Evidence or further ad uh Adverse Events uh warning about OIC serious serious side effects in patients with diabetes research studies have found higher risk of gallbladder liver and bile duct disease okay they also found inflammation of the pancreas again pancreatitis bowel obstruction and gastroparesis which is a shutdown of gastric movement again paralysis right literally the the um your gastrointestinal system just completely just stops you know paralysis basically okay so it it this is a serious condition okay because you literally you're not going to be able to absorb food so something to take a look at now at its worst food can sit in your stomach undigested for hours you know putrifying and bowels shut down with extreme complication if you end up with this paralysis okay so and this is where the symptoms the symptoms could be so bad that you can require hospitalization okay it becomes a chronic condition that can get worse over time and this is what has prompted lawsuits this is that that um gastric paralysis is where lawsuits will start starting to come out you know from because of that next there's been more adverse reactions as well adverse reactions reported included nausea vomiting diarrhea dehydration abdominal pain and constipation those reactions have occurred in more than 5% of patients with OIC other complications include uh kidney injury now yet be aware that OIC is in the process of gaining approval for treatment of chronic kidney disease in patients with type 2 diabetes so think about it for a second okay chronic kidney injury is one of the complications but they're proving it for C chronic kidney disease in patients with type two diabetes what could possibly go wrong with that I'm just saying I'm just saying okay pregnancy warnings the FDA recommends that women stop the medication at least two months prior to a planned pregnancy because the drug stays in their system for five weeks after the last dose and animal reproduction studies show potential risk to The Unborn from exposure to semaglutide during pregnancy so those of you who want to have kids I wouldn't mess with this at all I get it if you want to lose the weight but you know again if you're on this type of stuff I you know you better detox I talk about detoxing for at least six months before you have a child just overall now imagine if you're taking this so again keep that in mind also the FDA adverse events reports it has over 45 different types of gastrointestinal symptoms reported to the FDA and its Adverse Events reporting system so basically what they're saying is that we don't know the long-term side effects of 94% of the glp1 analoges okay what it what does it do to normal physiology after a couple of years of use or longer right and then here's the other question and you know to think about when you're looking at these types of things um what happens when you get off it let's say you you use it you lose a bunch of weight and then you get off the drug what happens what happens to your system does it just go right back or do you do you now change your um do you do you change your way of doing things right do you change your eating habits do you change your exercise habits to try to keep the weight off now because a lot of people have trouble just taking the weight off in general right so these things are actually just doing that but now let's say you do that and you get to the weight you want to get to does that mean you change your your ways it's a good question right what are the long-term effects we really don't know because what's what they're doing now is postmarketing studies so they Market the drug they get it out there people are starting to use it and then they do studies post marketing and then this is where you find out oh by the way this this is all the stuff and this is all the crazy stuff that's happening so you know you guys can kind of see it for yourself I just gave you the highlights of the article but definitely read it but definitely keep track of this and again those of you who are on the fence thinking about using this type of thing you know do your homework as I always say with anything do your homework don't take my word for it read the articles look it up you know talk to your doctor whatever and see if it's worth it to use these type of things is it worth it you again we don't know what all the side effects are I'm sure there's going to be more as as time goes along we don't know