What We Got WRONG About Vitamin D for Osteoporosis | NEW RECOMMENDATIONS

I recently published a video on my favorite calcium supplement for osteoporosis and this created a bit of a controversy we actually had a record number of questions and comments after this particular video which was super fun we love those comments keep them coming but one area I'd like to dig into with this topic is not to repeat that same video but a lot of the questions had to do with the pairing of the alal product alal plus with the D3 complete there were a lot of questions because I recently did a video not recently but historically did video on the product called protect 5 which is a very similar product to the D3 complete so I wanted to share with you our thought process behind that but also some of the lab values that we've seen go along with each of the supplements and and what really drove uh this decision was some research that we've been going through over the last uh several months to to a year so if you're using either of these products or you're just looking for the best combo of supplements to be the base the foundation of your bone health stack stick around also if you're using either of these products and have a story to tell us again we love those comments we love those questions so please leave those on YouTube Three 2 1 here we go [Music] so if you're new to this channel you may want to watch the video that I'm referencing the best calcium supplement for osteoporosis 2024 update and New Perspectives on calcium so that video goes through in full depth the kind of Full Circle that we've gone on our calcium products but so the question that really stems from that video is because the algae cow plus product has 1,600 IU of vitamin D in it we got a lot of questions of well if I add this to my current supplement stack and I'm already taking vitamin D and my going to get too much vitamin D especially if they were already taking the protect 5 so for those that are taking the protect 5 we know that there has there is either 5,000 or 10,000 IU of kic calciferol or vitamin D3 which is the preferred form of supplementation of vitamin D if you're going to take it depending on your genetics depending on a lot of variables uh how you consume it what you consume it with Etc that 5,000 or 10,000 can be a lot of vitamin D can be too much vitamin D and I want to share with you some of the lab values that we've seen in our patients that are on some of these products when they're paired with other products and what happens to the labs and again how that has led us to make some changes in the products that we're pairing together all right so first let's go over the product that we had recommended previously which is protect plus there's protect plus 5 and protect plus 10 one has 5,000 one has 10,000 IU of vitamin D otherwise they're the same product and the benefit of this product as I've previously mentioned is that it's a great product to get all of the fat soluble vitamins in one place the ingredients of this product include real vitamin A or activated vitamin A in retinol petate with mixed catenoids at a 3 milligram dose which is a pretty good dose vitamin D again as I mentioned before vitamin E as Alpha tocopherol and mixed copals so for those not familiar there are four different copals in vitamin E and you really need all of them and this is pretty relatively new research most vitamin E supplements just have Alpha tofol Vitamin K is really important as most people know and what I loved about the protect 5 is that it has 300 micrograms of K2 is mk7 the longer lasting K2 it is this special form this uh patented formula called K2 vital that is an all trans form so it should all be active uh versus the the mixed form of K2 as mk7 and then lastly astrogenesis and Panax and that promotes uh absorption and delivery of the fat soluble vitamins across the stomach and the gut so it's a really cool product and that's what I loved about it and we used it for a long time I took it myself um prior to this product we would have to recommend three different things to get that combination of stuff so it was a really great way to put everything into one capsule and and um you know we used it on a lot of our patients so our patient experience is that this is very powerful and it really increased 25 hydroxy or vitamin D in the blood uh I'll explain more about that in a second what I really liked about it too is that the quality of the ingredients were second to none and and we actually created a that video specifically for it and we ran a uh promotion to raise money uh for a group called CMA Warrior a company that helps veterans matriculate into civilian life and we were able to raise over $2,000 as a donation uh for CMA Warrior which was a really great way to promote a product on YouTube so let me show you what happened um let me show you why we made this switch but before I get there and I tell you what we saw in our Labs that really drove us to make this switch if you haven't taken our bone health master class yet I strongly encourage you to do that because it will help you to put together a comprehensive bone program for yourself if you are concerned about your bone health or have osteoporosis if you're looking for the link for that it's in the description on YouTube or if you're on a podcast you can just go to Optimal human health.com and you can find the link there okay so what happened on our Labs that was a little bit concerning well first of all vitamin D goes up a lot and that was what we were trying to do right so our goal was achieved well the answer is kind of so we started using protect 5 in our practice so what happened well yeah vitamin D went up and it went up a lot so our goal was achieved right well yes and no so around the same time we started using this product I was doing more and more research into Vitamin D I met and talked with morly Robbins who I have a couple of videos with uh not specifically about vitamin D but about copper and iron metabolism and one of the areas that he focuses on in his book cure your fatigue is is vitamin D the impact of consuming kic calciferol uh which is the again the D3 that is found in supplementation what that does to other nutrients as you consume it and especially as we start to aim for higher levels of it and it turns out I'm not the only one who is questioning getting these really high levels of vitamin D but certainly all of us are in the minority but let me be very clear especially for people that have osteoporosis I think we do need adequate vitamin D and frequently to get that through supplementation however in all of this research I was not able to find any study that clearly show benefit of vitamin D as an intervention meaning kic calciferol as an intervention in a trial more than 400 international units a day and that was the Women's Health Initiative that was you know 25 years ago 22 years ago so I think there's a lot of misinformation about vitamin D in the media by a lot of doctors now there are a lot of studies looking at the associations between blood levels of 25 hydroxy in conditions like cancer immune Health Etc but the intervention studies always fail to show benefit for anything other than osteoporosis why would that be well vitamin D is a pretty complex vitamin and here's a couple of things to consider kic calciferol that D3 that you find in supplementation it's only one form of what really should be called a hormone so it's really not a vitamin and if we want to call it hormone D we could look at it like this hormone D has the same cholesterol precursor as many other hormones it acts like a hormone in the body like many of the hormones it has many forms cholic calciferol and supplements is not the same as quote unquote col calciferol in the body it has to be metabolized which requires magnesium and that puts a strain on our already depleted source of magnesium so the more and more cholic califer taking supplementation the more of an impact you're going to have on your magnesium levels which for most people are already depleted Additionally the benefits of the hormone D come from the action of the active form which is called 125 hydroxy D or calcitriol 125 hydroxy is not measured by most doctors and it does fluctuate up and down more rapidly than 25 hydroxy which is why the recommendation was always to do 25 hydroxy and not 12 125 hydroxy 255 hydroxy is more steady state so it doesn't matter when during the day you test it it's going to be pretty much the same 125 can go up and down but 125 is the active thing that we actually care about and it's not only just the 125 level but also its impact on the vitamin D receptor which is in the cell and again this is why it functions more like a hormone than a vitamin so it's intuitive that taking 25 hydroxy or something that raises 25 hydroxy called kerol would end up actually raising the active form but this is kind of like assuming that eating cholesterol raises blood cholesterol or that eating fat makes you actually fat biology is more complex than that obviously we know that people that go on ketogenic diets high in fat generally aren't getting fatter people that are eating and we've now seen this over and over again in research people that eat higher levels of cholesterol actually some most get lower levels of blood cholesterol it's not the cholesterol our metabolism is more complex than that Morley's research is really interesting in his book it suggests that vitamin D supplementation has been falsely recommended and that vitamin D deficiency is not nearly the issue that we have been led to believe some interesting components of this story include the work of Dr Michael holik he pushed for raising the reference range of 25 hydroxy D while simultaneously holding a patent on different forms of vitamin D supplementation so I don't know his intent and I'm not calling him out here but to me that seems questionable vitamin D deficiency certainly does exist and it has for a long time but it used to exist with the reference range of deficiency was less than 20 nanograms per ml so now we have practices like my own which used reference ranges up to 80 to 100 NS per ML and we've now lowered it down to 30 to 50 and that's because we find that deficiency truly is and always has been of 25 hydroxy less than 20 and so we find that most people are not actually that deficient and if they are that deficient it's actually a sign of an underlying problem it's not really the 25 hydroxy that's the point it's the fact that the 25 hydroxy is being drawn into 125 and 125 is high because there's something going on where your body needs that extra hormone D the last Point here is that in order for hormone D to do its work it needs vitamin A or retinol kic calciferol supplementation or vitamin D supplementation directly impacts retinol absorption so now we have in our practice been measuring biomarkers of retinol of vitamin D of 25 hydroxy 125 hydroxy and we now have compiled compelling data to show that the higher the 25 hydroxy gets usually from supplementation or always from supplementation the lower serum retinol will be so for me I find that we probably need to be consuming less vitamin D and we've adjusted our protocols to fit that so now let's take a look at the alal D3 complete okay so alal D3 complete so it is actually a really similar product it has has 550 micrograms of retinol petate so that again is vitamin A it has 2.83 mg of d alpha tofol and 25 milligrams of gamma tofol so two of the four tphols but also 50 milligrams of mixed toot trols what the heck are toot trols other than a fun word to say it's another form of vitamin E vitamin E actually has eight forms not four so it's four tphols four toot trols and then it also has three three different forms of vitamin K so the vitamin K and D3 complete is 1,000 Mig of K1 4500 Mig of K2 is MK4 the shorter acting but better studied vitamin K and then 50 mics of K2 is mk7 and it has a th000 IU of chical cerol or D3 so if you then pair that with aacal plus you're going to get another 100 micrograms of K2 as mk7 and 1600 IU a kolic calciferol so that makes a total of 50 mics of K2 as mk7 2600 IU of kolic calciferol so really that is what I consider a complete package starting point into products additionally something I've been reading about and thinking about with Vitamin K is that with K2 is mk7 you're really only getting one form I do think that is probably the best form but there is likely also a value of MK4 and K1 and so we're basically just covering all of our bases from vitamin K perspective and vitamin K dosing is relatively unknown space also like I said I like the too triols in addition to the toffer alls um because vitamin E is showing increased benefits specifically with that Delta tofol um as well as all the the mixed Tok triols so I hope that that demonstrates our rationale the biomarker issues that we've seen and what we are doing to create a plan moving forward we are going to continue to obviously measure these biomarkers we're going to see how these things improve but we have enough evidence at this point that I wanted to share this with our audience to let you know that there is some potential risk from a biomarker perspective of having too much vitamin D you've probably heard people talk about too much calcium and blood with too much vitamin D and that is a real risk but that happens at pretty darn high doses this is something that I see is going to happen at lower doses that a lot of people probably have at this point and lower levels uh in blood is what I mean if you haven't watched the other video on the uh my favorite supplement uh calcium supplement for Osteo process uh we do have a partnership with alal that I want to bring forward um and this is an affiliation but the benefit for you is that if you use the code oh10 or use the link in the description on YouTube you can get a discount on products like D3 complete alal plus strum Etc uh from alal so in conclusion we are always looking for the best products to help our patients these two products together are such a great starting point from a foundational perspective that it is really probably being used I think in all of our patients at this point if you want to learn more about the aacal products again watch that best calcium froso process video and then also we have a video on Boron uh which came out after the best calcium froso process video really um this was pushed because of the the amount of boron that's in that video uh and I was excited to uh share the research on Boron as well so remember that osteoporosis isn't the end but deciding to reverse it is a beginning now if you've already seen the uh master class and you want to learn more head over to Optimal human health.com and look for the bone foundations course it is our free course uh that will get you a lot more information of how to build a bone health program on your own um and again you can go to Optimal health.com for that I will see you on the next video this presentation is for General informational purposes only does not constitute the practice of medicine nursing or other Prof professional healthcare services including the giving of medical advice no doctor patient relationship is formed the use of this information and the materials linked to this presentation are at the user's own risk the content in this presentation is not intended to be substitute for professional medical advice diagnosis or treatment users should not disregard or delay obtaining medical advice for any medical condition they have and they should seek the assistance of their Health Care Professionals for any such conditions