Louis Pasteur
Louis Pasteur
Louis Pasteur (1822–1895) was a French chemist and microbiologist whose discoveries established the germ theory of disease and transformed medicine, food safety and public health. He began as a chemist, discovering molecular chirality through his study of tartaric acid crystals, before a request from local industry led him to study fermentation. He showed that fermentation and spoilage are caused by living microorganisms, and he developed pasteurization, the gentle heating process that still protects milk and other foods. His swan-neck flask experiments helped disprove the idea of spontaneous generation. Turning to disease, he developed vaccines against chicken cholera and anthrax, and in 1885 successfully treated a boy bitten by a rabid dog with his new rabies vaccine. The Pasteur Institute, founded in Paris in 1887, continues his work in research and the prevention of infectious disease.
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Pioneers of Hygiene and Germ Theory
Ignaz Semmelweis showed that handwashing by doctors sharply reduced deaths among new mothers, and Florence Nightingale improved survival in military hospitals through sanitation and careful statistics. Louis Pasteur demonstrated that microorganisms cause fermentation and disease, Joseph Lister applied his findings to introduce antiseptic surgery, and Robert Koch identified the bacteria responsible for tuberculosis and cholera.
Pioneers of Vaccines and Antibiotics
Edward Jenner introduced vaccination against smallpox in 1796, using material from cowpox. Louis Pasteur developed vaccines against anthrax and rabies and proposed extending the word vaccine to all such protections in Jenner's honor. Paul Ehrlich, seeking a 'magic bullet' against disease, developed Salvarsan (1910), often called the first modern chemotherapeutic drug. Alexander Fleming discovered penicillin in 1928, and Jonas Salk's polio vaccine, announced in 1955, was never patented.
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