Are Americans being prescribed antidepressants too quickly—and what happens when medication doesn't address the underlying causes of depression?
In this excerpt from The Brief: Insights From The Inside, Shabbos Kestenbaum speaks with Dr. Josef Witt-Doerring, a former FDA medical officer, board-certified psychiatrist, and founder of TaperClinic, about psychiatric overprescribing, antidepressant side effects, and the pressures facing doctors.
Dr. Witt-Doerring explains when he believes medication can be appropriate, why lifestyle and relationships matter in mental-health treatment, and how financial pressures can affect patient care. Shabbos also shares his personal experience with anxiety, depression, and psychiatric medication.
So on another concerning note,
according to the American Enterprise Institute, 30 years
ago, the majority of men, this is close to 60%,
they reported having at least six friends.
Today, the number has been cut in half.
Only 25% have close friends.
15% of adult men in America have no friends at all.
That's a five-fold increase from 1990.
Amongst my generation, Gen Z, 30%,
30% of Gen Z men have zero friends at all.
What is happening?
and i know we've alluded to the medical
and scientific problems with suicidality with
depression with anxiety but just from a friendship perspective
this is this is insane i mean i can
speak i'm a millennial
and i can kind of speak speak to how this has impacted me i i feel like
i've right now my whole life has been dominated
by work i mean that is the cultural values going
on and you know i often get up and leave
and i leave my friends behind and then i often find
myself socially isolated from others um i
also think you know the there's a lot of political
polarization going on right now there's a lot
of canceling going on online and i also think it kind
of scares people to open up and just be themselves
and that can create barriers but i'm gonna push
this back on you and you don't have to be an answer
but i'm just i'm just so curious i was
like what do you think is going on as you know someone down
in the the gen z trenches what do
you see happening? As the token Gen Z representative
for this conversation, I would say it's social
media. I mean, why do you need to have a physical relationship
when you have pornography in your
basement? I would say it's also a fear of cancel culture
and a blowback to me too. I'm scared of
asking that pretty girl out because I don't want
to have any type of professional blowback or social
isolation as a result. I do think to get a little political,
men have been stigmatized and told that
they are inherently due to their gender,
due to their race, are bad or racist or misogynistic.
And when you keep telling young people that thing,
they're actually going to believe you.
So I think the solution is not just medical or scientific.
It's also cultural and political.
I think, yeah, I mean, we're coming out of a period where
for the last 10 years we've been told, you know,
if you're if you're a man, especially if you're a white man,
you're privileged and you're kind of racist.
And you better watch out, buddy, because, you know,
if you say something that could even be perceived in a negative way,
you know, we're going to come after your job.
So you made this point that psychiatric medication does have potential
side effects. We know that this includes sexual dysfunction.
We know this includes emotional blunting.
We know that this includes dependence
and other long term complications. But I sort of want you
to preempt the nasty comments on YouTube who say, hang on a second,
are you really telling me that someone who is depressed
or someone who is anxious should not be on any medication at all?
Like, how do you know to draw the line between when someone needs
to just go on a walk, needs to solidify relationships versus no,
this person really has a chemical imbalance.
We really do need to treat them with medication.
Yeah, we need to move back to a common
sense approach to using the drugs.
No drugs are bad.
I mean, they're essentially tools that you have in a toolkit to use.
But if you OK, so if if you come to me and you are saying,
hey, I'm depressed and I just put you on Prozac,
did I did I really help you if I don't understand your life?
Because let's say I dig a little deeper and I find out that you
walk 4,000 steps a day, that you don't move your body, that you,
you know, rarely get out of the house before 11 a.m. in the morning.
You kind of wake up and you flip open your laptop
and, you know, you go to work.
You know, you also drink several cups of coffee a day.
You're using nicotine products.
You drink a couple of drinks to go to bed at night.
and and and yes i could say well you know
technically you meet criteria for major
depressive disorder because you feel terrible
and you're eating bad food and put you on the
Prozac is that really good medical care it's
not that's crap i mean that's you you wouldn't
want anyone to have that and that's pretty much what most people
in our country are getting today
they are getting care from uninvested doctors
who do not understand their lives because all of that
stuff getting that fixed you know moving
your body more cleaning up your diet exercising getting out
into nature early in the morning to set up
your circadian rhythm properly spending time outside
all of those things are the things
that actually make people feel better and when we just paper
over them with drugs that don't address
those problems they just fester and people get worse
now if you come to me and you say hey dr yosef i've done all
those things i'm super invested in
my healthcare. My relationships are good.
I've got meaning and purpose in my life and I'm healthy.
I'm still feeling bad. I'll say, you know what?
Let's use some Lexapro. Let's use some Prozac.
You've done all the non-drug alternatives.
You've really tried to get to the root cause. We can't
find them. Now let's treat this more like a genetic depression
and just, you know, we'll talk
about the risks and benefits and we'll use it in that way.
But that's like, that doesn't happen to
anyone right now. Like most people, you know,
they just, they come and say I'm depressed and they get
a drug. And so that's, that's my problem with the current system.
You know, Dr. Midd, I shouldn't
say this, but the real reason we booked you
is I essentially wanted a free consultation because
I'll just say that, you know, post October 7th,
I was diagnosed with anxiety. I was diagnosed with
depression and I was given medication, a heavy dosage, I would say.
And I gained a tremendous
amount of weight. It didn't really make me feel better.
And I would just add that anecdotally,
what you're saying really resonates
because what did in fact help was going on walks,
was making friends, was solidifying, you know, previous relationships.
It was things like that.
So obviously, every individual is different,
but I very much relate to what you're saying.
But I do have to ask, when you talk about these doctors
who are overprescribing or they're
treating an algorithm rather than a patient,
I mean, most individuals watching this would
say, well, you know, I know my doctor.
My doctor, for the most part, has my best interests at heart.
So where is this coming from?
Is this really because of the pharmaceutical companies?
Is this because of bad policies or politics?
Like, why are they doing this?
These are not bad people.
Yeah, Shabbos, it's two things.
The first thing is the pharmaceutical industry.
Now, when it comes to antidepressants, I mean,
these are some of the most successful drugs of
all time. I mean, they made Eli Lilly
a billion-dollar company, and they've done the same
for many others. When you essentially have like five
or six different companies selling these
drugs, you have billions of marketing spend,
which are trying to control the narrative about
these medications. And the most effective thing
that they ever did was convince the public that
depression is a genetic problem.
It's medical in origin, and it needs to be treated by drugs.
That is not true at all. It is not backed up by the medical literature.
And depression is much more broad
and should be addressed in more holistic ways.
So that's the first thing they did. They convinced the public
and the doctors to look at depression in that way.
The second major player is simply an economic one. Back in the 90s,
health insurance companies conglomerated and they negotiated
with doctors on how much they were going to get paid per visit.
That number was so low that doctors now have to see people
with seven minutes of face time to essentially make
the medical practices economically viable.
and so you have these lovely people these are doctors
in our families these are our friends
these are our parents who essentially are trying
to do a job with a hand tied behind their back
now if you're seeing if you have to see like four
or five people an hour you have a patient panel
of 2,000 people how well can you understand
their lives you can't it's effectively impossible
and so these good people they do what they can
in their limited time which is essentially
oh you filled out this questionnaire you're depressed
and i know that there's an FDA approved
drug for this. Let me just prescribe that.
And so that's, that's essentially what's happening.
These aren't bad people.
They are just, you know, they just don't have the time to do the job
properly. Hey, if you enjoyed that clip,
make sure you click the link below to watch the full
episode of this week's The Brief.