He Spent 100 Days Underwater and Became 10 Years Younger?

Joseph duri is a retired us naval officer who spent 100 days in a port submerged in the Atlantic Ocean after he emerged his medical exams found he had gotten healthier and his tiir that typically shorten with age had gotten 20% longer based on that knowledge he was 10 years younger his stem cell count had also increased which is another Hallmark of Aging that's quite an interesting outcome is living underwater really the key to reversing aging and living longer in this video I'm going to look at Joseph's experiment and talk about his results Joseph duri has been breaking the world records for the longest time being spent underwat several times over the last few years in 2023 he spent 100 days underwater in Florida his P was 22 ft or about 6.7 M underwater Joseph also known as Dr deep sea has a PHD in biomedical engineering from the University of South Florida and he's a president of the undersea oxygen Clinic while he was underwater he held online courses to over 5,000 students worldwide his main goal is to research how humans are able to adapt and survive in extreme conditions such as being underwater but he also researches age related diseases and how to make humans live longer his hypothesis is that by being underwater and being exposed to this increased pressure you're able to slow down and prevent some of the age related diseases and extend human lifespan after he resurfaced from his 100 day experiment underwater in 2023 they found that Joseph had shrinked by half an inch which is about 1.27 cmet however he apparently grew back to his previous 6'1 after 9 months of being on land his cholesterol inflammation and Sleep Quality improved as well his cholesterol went from 272 to below 200 his inflammatory markers decreased by about 50% and he did 19 psychological tests while being underwater and they all improved my first reaction was that his cholesterol went down his inflammation went down because he probably lost weight however Joseph is a scientist and he did say that he didn't change his diet during the experiment which is interesting so he was eating the same foods but I think that he still probably ate a little bit less and based on the reports he did lose a little bit of weight which is impossible without being in a calor deficit calor restriction and weight loss are going to improve all your biomarkers even if you're not changing your diet and even if you're eating a processed food diet Joseph was also exercising in the port for an hour or 5 days a week with resistance bands which he might have not been doing before let's talk about the tares and stem cells tare shortening and stem cell exhaustion are one of the main Hallmarks of Aging telr are these protective caps on top of chromosomes that protect DNA with age your tiir shorten which is a sign of Aging the total length of tiir hasn't been found to be as relevant to aging and Longevity as the speed of the tiir shortening and tiir dysfunction accelerated til shortening is associated with many chronic diseases like cancer neurod degeneration and heart disease but having super long TI itself doesn't appear to be that important the unhealthy lifestyle like obesity smoking and chronic stress shorten tiir tilr can be lengthened via the activity of an enzyme called tase however tase has also been seen to extend the lifespan of cancer cells cancer cells are characterized by Tas activity so it appears that it's more important to prevent T shortening because of unhealthy lifestyle instead of trying to extend them stem cells are another Hallmark of aging and they come diminished with age stem cells are the earliest type of cell in a Cell lineage and they can become any other cell in the body that makes stem cells very important for healing and repair there's no evidence that injecting stem cells or boosting stem cells is going to make you live longer however there are some studies showing potential for various diseases right now the only FDA approved stem cell therapy is hematopoetic or blood stem cell transplantation it's used to treat patients with Cancers and disorders that affect the blood and immune system what Joseph is really researching is the benefits of hyperbaric oxygen therapy or hbot his hypothesis is that this increased pressure environment of being underwater has health benefits and by using hyperbaric oxygen therapy you can mimic those effects hbut is a medical treatment where you're breathing pure oxygen in a high press chamber the medical conditions that are approved to be treated with hbot include carbon monoxide poisoning Central retinal artery occlusion decompression sickness skin grafts thermal Burns and others there's no evidence that hbot is going to cure cancer autism Alzheimer's heart disease stroke or other chronic diseases a 2020 study did find that Hyperbaric auction therapy for 60 daily exposures among 35 healthy 64 and older adults increased telr length and various immune cells like natural killer cells by over 20% another 2022 review also showed that hbot can stimulate stem cell proliferation angiogenesis which is the growth of new blood vessels suppresses cell inessence and lowers inflammation however there are no clinical trials looking at the effects of hbot on any of the age Rel diseases or longevity so it's very early to say if hbot will have any of those effects there are plausible mechanisms though there are interesting things that happen when you're doing hbot but we will still need some actual clinical trials to look at those effects mechanistic reasons can only take you so far what matters more are the actual human outcomes Joseph has a vision that people will be able to take two we vacations in underwater hotels where they're exposed to the increased pressure and their health will improve well let's see it's of course an interesting idea and I think a lot of people will you know do it but to answer the question that I asked in the beginning of the video does spending 100 days underw make you 10 years younger well Joseph's Health markers apparently did improve but that could be because of just eating less and losing weight you would need to do this experiment together with a controlled feeding trial where all the calories are equated before and after the submersion the same applies to the tillar and stem cells losing weight can improve those markers as well so to sum it up it's obviously very interesting experiment I personally probably wouldn't do it with the evidence we have right now but it's certainly something worth researching more maybe you can mimic those effects with regular hyperbaric oxygen therapy but at the moment I wouldn't book a holiday in an underwater your hotel other than that thanks for watching this video make sure you click a like And subscribe for future videos about living longer and staying healthier my name is SE stay optimized stay empowered