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Last Friday, there was a, you can say, surprising statement that was made by Joe Biden.
After finishing his Pilates and spin class while he was on vacation over in Lake Tahoe,
well, Joe Biden came out to speak briefly with a gaggle of reporters.
And during that brief interaction, he said that he's planning to request more money from Congress
in order to develop a new coronavirus vaccine. And he added that it will be likely recommended
to everyone, regardless of whether they've taken the previous shots or not. Take a listen.
So, as he mentioned in that brief statement, Joe Biden signed off on a proposal to be sent
off to Congress in order to request new funding towards developing a new vaccine, quote,
that works. Furthermore, as you just heard, he said that it will likely be recommended to everyone
in the country, regardless of whether they've gotten a shot before or not. Now, that statement
of his, it came as a response to the rise in COVID cases, at least that some regions in the
country are experiencing, a bit too perfectly timed with the upcoming election. Here's specifically
how the Hill publication describes the situation, quote, new vaccines containing the version of the
Omicron strain XBB 1.5 are already being developed by Pfizer, Novavax and Moderna.
However, the virus's continuing mutation will likely necessitate updated vaccines.
Although whether or not this requested funding will actually come through is another question.
For your reference, last fall, Joe Biden likewise asked for over $9 billion more from Congress for
COVID-related measures, but that request was denied. Regardless, though, since we're generally
on the topic of government investment, there's something else worth mentioning. The fact that
outside of COVID, the federal government has recently invested $24 million in mRNA technology
to treat other things like cancers, autoimmune disorders, infectious diseases, and so on.
Specifically, many people aren't aware, but the Biden administration recently launched a new
biomedical research agency. It's called the Advanced Research Projects Agency for Health,
otherwise known as ARPA-H. And according to a statement that came out of the White House
just last week, it's this exact agency, which is providing the $24 million investment to the
project. And that project just for reference is called the quote, curing the uncurable via RNA
encoded immunogen tuning project. And the reason that it has such a weird long name is because they
wanted the acronym to read cure it. And so the project is essentially the cure it project. And
according to that statement from the White House, here is what this $24 million investment in mRNA
technology is supposed to accomplish. Quote, last year, as part of his unity agenda, President Biden
worked with Democrats and Republicans in Congress to establish and fund ARPA-H to drive breakthroughs
to prevent, detect, and treat cancer and other diseases. Through cure it, ARPA-H is now moving
aggressively to deliver on their mission and to advance the goals of the Biden cancer moonshot
and the president's unity agenda. The aim of cure it is to create a toolbox of mRNA and related
technologies that could be used to quote, unquote, turn on helpful immune responses,
such as prompting immune cells to target and attack cancerous tumors. And it's worth mentioning
that this particular project is quite important to Joe Biden's presidency, evidenced by the fact
that while he was still on the campaign trail, he promised his supporters that if he was elected,
he would cure cancer. Take a listen. If I'm elected president, you're going to see the
single most important thing that changes America is we're going to cure cancer.
Regardless, setting that aside, this cure it project is being led by a team over at Emory
University in Atlanta, in conjunction with another team over at Yale University. And in terms of the
specifics of this mRNA vaccine cancer research, here is what the Emory University officials wrote
about it. Quote,
Immune modulation is a way to enhance the body's immune response. The conventional methods of
immune modulation, which are vaccines, antibodies, small molecules, and cell-based therapies,
face limitations in their ability to engage immunity and manufacturing complexity. To
overcome these limitations, researchers at the Emory University's Sant'Angelo lab will develop
a novel class of mRNA-based drugs to precisely turn on, or turn off, genes in individual immune
cells. In other words, the mRNA-based drugs will directly target immune cells within the body,
prompting the creation of target proteins that may improve immune function and fight against cancer.
Now, alongside Emory University, this federal grant will also be shared with researchers over
at Yale University. And there, they published a much more detailed outline for what these
researchers are trying to accomplish and which specific immune cells they're trying to activate.
Quote, Combining Emory University's expertise in mRNA and Yale University's expertise in
dendritic cells, the most prominent initiators of selective immune reactions, the multi-institutional
team will be studying how to advance technology from the Bergerning mRNA vaccine field to program
dendritic cells to produce therapeutic immune reactions with personalized cancer vaccines as
the ultimate goal. And just to pause here for a super quick moment, if you've never heard of them
before, dendritic cells were first discovered back in the year 2011. In fact, the people who
discovered them won the Nobel Prize for that particular year in 2011. And these dendritic
cells, they've been found to play an important role in the body's immune response. They basically
degrade pathogens in our bodies so that our body's T cells can come in and recognize that pathogen
and be able to market for the future. So that in the future, T cells know to degrade that exact
type of pathogen. And from what I've read, these dendritic cells appear to be the frontline shock
troops of the immune system. They come in, smash the pathogen, and then the T cell comes in and
absorbs all the information so that they know in the future that that's a pathogen they should
be looking out for. Regardless, the Yale University statement continues. Quote, The teams are working
together to use mRNA to program the dendritic cells to process antigenic proteins, thereby
triggering selective immunological responses. Dendritic cells are key players in the immune
system's capacity to destroy cancer, serving as the ignition of the immune system. For decades,
dendritic cells have been considered the tantalizing holy grail for initiating preventative
and therapeutic immune reactions. Investigators envisioned that by loading an individual's
dendritic cells with antigens in the lab, they could develop into cellular personalized vaccines
for those patients. But until scientists could understand how the body produces dendritic cells,
where and when they are needed, artificial methods were required to produce them outside
the body in order to then arm them with the antigens that could serve as the GPS directing
them to the enemy, uncheck cancer cells and dangerous microbes. However, now these Yale
University researchers are hoping to combine the mRNA knowledge of the other researchers
over at Emory University to be able to pre-program these dendritic cells to fight cancers that are
specific to an individual. Only time will tell whether this approach of theirs will actually
bear fruit. If you'd like to read more about either the specifics of this Cure It project,
or if you'd like to read the description that came out of Yale University, it's pretty good.
It's actually pretty long and it goes into pretty good detail. I'll throw all these research notes
down into the description box below this video for you to peruse at your own leisure. And I will
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