Levothyroxine is a synthetic form of thyroxine hormone, or T4, which is structurally identical to the endogenous T4 produced by the thyroid gland.
Following administration, levothyroxine is converted into T3, the active form of thyroid hormone, in peripheral tissues. T3 binds to thyroid hormone receptors in the cell nucleus and alters gene expression, thereby regulating metabolism, protein synthesis, and growth in virtually all tissues.
The adverse effects of levothyroxine are usually dose-related and occur due to over-replacement. Common side effects include, Palpitations, tachycardia, and cardiac arrhythmias. Anxiety, tremors, and insomnia. Weight loss, heat intolerance, and excessive sweating. Diarrhea. Osteoporosis, particularly with long-term overuse. And Menstrual irregularities.
Side Effects of Levothyroxine Levothyroxine
is a synthetic form of thyroxine
hormone, or T4, which is structurally identical
to the endogenous T4 produced by the thyroid gland.
Following administration, levothyroxine is converted into T3,
the active form of thyroid
hormone, in peripheral tissues.
T3 binds to thyroid hormone receptors in the cell nucleus
and alters gene expression, thereby regulating metabolism,
protein synthesis, and growth in
virtually all tissues.
The adverse effects of levothyroxine are usually dose-related
and occur due to over-replacement. Common side effects include
Palpitations, tachycardia, and cardiac arrhythmias,
anxiety, tremors, and insomnia, weight loss,
heat intolerance, and excessive sweating,
diarrhea, osteoporosis, particularly with
long-term overuse, and menstrual irregularities.
