Why is Gen Z struggling with anxiety and depression—and are Americans relying too heavily on psychiatric medications to address the mental-health crisis?
In this episode of The Brief: Insights From The Inside, Shabbos Kestenbaum sits down with Dr. Josef Witt-Doerring, a board-certified psychiatrist, former FDA medical officer, and founder of TaperClinic, to examine antidepressants, psychiatric overprescribing, and why so many young Americans are struggling with their mental health. Dr. Witt-Doerring challenges the way depression is diagnosed and treated, discusses the potential side effects of SSRIs, and explains why sleep, exercise, diet, relationships, and social connection deserve greater attention alongside medical treatment.
The conversation also explores Gen Z loneliness, declining friendships among young men, social media, and the growing looksmaxxing trend. Shabbos opens up about his own experience with anxiety, depression, and psychiatric medication as the two discuss a fundamental question: Are we addressing the underlying causes of mental-health struggles—or simply treating the symptoms?
Watch more episodes of The Brief with Shabbos Kestenbaum for quick insights from the inside.
This conversation explores Dr. Witt-Doerring's professional opinions and experience. Psychiatric treatment should be individualized; anyone considering changing or stopping prescribed medication should consult their clinician.
42% of Gen Z Americans have been diagnosed
with a mental health condition.
These numbers are batshit crazy.
What in the hell is going on with Gen Z?
We're in the midst of a medical and psychiatric crisis.
Physically and mentally, they're doing very poorly.
If we're spending billions of dollars more in mental health treatment,
how can we have such bad outcomes?
Our current system right now is really designed to just dish out pills.
What are some of the harmful effects of these drugs?
Along with blunting our hunger drive, it blunts our motivation.
They're just a band-aid for a greater lifestyle problem.
So this might sound a little strange,
but should Gen Z men be drinking more alcohol?
Dr. Whitdering, appreciate you making the time.
Thanks, Shabba. It's great to be here.
Doctor, I want to get straight to the incredibly
concerning numbers from the Walton Family Foundation.
It has found that 42% of Gen Z Americans have
been diagnosed with a mental health condition.
That is double the rate of older adults.
61% report feelings of or have been diagnosed with anxiety.
40% experience depression. 25% have been formally diagnosed with ADHD.
These numbers are batshit crazy.
What in the hell is going on with Gen Z?
So I think this is real, what is happening right now.
I think we're in the midst of a medical and
psychiatric crisis going on right now.
And I think most of it has to do with living out of alignment
with with how we are designed and so um you know
when we look at gen z i mean they are spending so
much time on social media uh these days um um and i mean there's
also like health problems going on
there's you know 70% of our country is overweight
or obese on average people are getting around
4,000 steps a day which is very low
um younger generations tend to be more um on tech all the
time and so you know they'll wake up they won't
go outside they don't see the sun um they spend
all their time inside and so that i think physically
and mentally they're doing they're
doing very poorly so i i think a lot of it comes down
to to just completely living out of alignment
with how we were designed.
So to your point, Dr., suicide deaths have increased
by 62% since the early 2000s.
We also know that antidepressant use has surged by more than 500%.
So what I'm trying to understand
is we know psychiatric diagnoses continue to rise,
particularly, again, amongst my generation.
But then the obvious question is,
if we're spending billions of dollars more in mental
health treatment, how can we have such bad mental health outcomes?
Well, we're spending money in bad ways.
And, you know, the mental health industry,
it's like, it's almost $400 billion a year.
I mean, it's crazy.
Like that's, you know, I think defense spending is around $900 billion.
So spending like, you know, half as much on mental health
that we spend on like our national defense.
And so the question about like,
what are we getting for that money is a really good one.
Well, we're not getting a lot.
our current system right now is really designed
to just dish out pills in a major way. And people
have seen this when they've gone to see their doctor.
They'll see their doctor, they'll get
diagnosed with depression or anxiety.
Usually it's off a checklist. Oftentimes, and this is just
baked into it, the doctors won't have time
to really understand their lives. Most psychiatric
meds are prescribed by family medicine doctors
who spend on average around seven minutes of
face time in the visit.
This is just the reality of the commercial insurance model where the
doctors, that's the time that they have to spend
with them if they're going to make ends meet
financially for the practice.
And so when you have a practice like that, what often ends up
happening is you understand nothing about your patients.
You diagnose them with checklists and
you treat them with algorithms.
And the biggest algorithm that we have is, oh, you're depressed,
let's get you on an antidepressant
and so oftentimes people just end up on these medications
they get limited attention to fix
their the underlying causes you know many of which i
mentioned a moment ago and so people fester in their medical
and psychiatric problems kind of
blunted with drugs and and they just never get any better
and ultimately if you don't actually
address why someone is feeling unwell or depressed,
it leads towards suicide.
So to me, RFK Jr., Health and Human Services,
the Maha Make America Healthy Again movement in
general, they kind of make the argument among many
that America is being overprescribed. Would
you say that's an accurate diagnosis of the problem?
Are Americans being overprescribed?
Is the solution to everything just throwing pills at the problem?
I mean, absolutely.
I mean, we are not doing fundamentally normal things that we know work
on mental health. I mean,
we have let our health care be taken over by moneyed interests. And who
are the two biggest players? Well,
it's the pharmaceutical industry. Clearly, they have a
commercial incentive to make us think about
our life problems in a medical lens because they have
the drugs for it, whether it's the GLP-1s or the SSRIs.
The other big group are the doctors. I mean,
doctors are also heavily invested
in essentially wanting patients to look at their problems with
the medical lens so they come to the doctors
but when it comes to mental health this has really led
our country astray because it has created
the impression that a lot of things that are actually
better than the drugs and safer than
the drugs you know whether it's dietary intervention movement
getting enough sleep and having healthier
relationships finding meaning and purpose
people look at that as oh yeah that's like
the mild stuff you know that's for the mild depression
That's some alternative stuff.
But for the like the serious genetic stuff, you know,
crack out the drugs, you know, that's what we need.
And that is completely false. You know, the the other stuff
is is what actually gets people sustainably well in the long run.
Doctor, there's a lot there to unpack,
but just because you mentioned GLP-1, I want to
focus on that very briefly.
We have seen the explosion, not just in popularity,
but the actual usage of GLP-1 drugs, chief
among them, perhaps, Zepbound, Ozempic.
But you make the argument, as do many doctors,
that this could actually be linked to depression,
anxiety, suicidality.
Can you just walk me through that?
What are some of the harmful scientific
and medical effects of these drugs?
Oh, sure.
Yeah, we can talk about that,
but I'm going to take a step back and talk about why there
is a need for GLP-1s in the first place,
because I think this is great for context, Shabbos, is
we use food like drugs in this country.
I want to be really clear about that. These foods are
designed to essentially be calming agents.
When you're going through your unhealthy life and
you're feeling unwell and you're feeling irritable,
you reach out for a bag of ultra-processed food
or, you know, something that's salty, sweet,
or has a lot of fat in it, and it calms you down.
You know, that's the way that a lot of the food is designed.
You know, 60% of the calories that
kids are having these days are coming from ultra-processed foods
because it's easy and
it also pacifies them.
And so now we have the emergence of a drug that is, you know, it's not
addressing the reason why we're emotionally eating all the time,
you know, which really
has to do again with living out of alignment
with with how we were designed to live it doesn't
address that it blunts our ability it blunts off our hunger drive
and and so that's that's what
it's doing that's why people are losing weight
and along with blunting our hunger drive it blunts
our motivation as well um and that's where people start talking about
this thing called Ozempic
personality, where they just feel meh.
They just feel unmotivated to do anything. And there are a
lot of these mental health problems.
So again, GLP-1s, they're just a band-aid for a greater
lifestyle problem that's going on.
So this might sound a little strange. I'm not necessarily
advocating for this, but NYU marketing professor,
I'm sure you saw this, Professor Scott Galloway,
he essentially argues that Gen Z,
particularly Gen Z men, should actually be drinking more
alcohol in social settings.
He says the point is not about getting drunk, but it's about
encouraging physical togetherness,
reducing social isolation, breaking through digital
screens to build actual real-world human connections.
In my view, the worst thing
that's happened to young people
is the anti-alcohol movement. I've had Huberman on,
who I'm a big fan of, and Antje on,
and my point is that the risks to your 25-year-old liver
are dwarfed by the risk of social isolation.
In sum, think of all the amazing relationships
you've had in your life and be honest did alcohol play
a role in some get out drink more and make a
series of bad decisions that might pay off yeah
i'm just curious should gen z men be drinking more
alcohol yeah he's spot on there i mean kids
are spending on average around five hours on social
media a day and so when we think about like where does
that where could that time go well
previously that time was spent outside
in the sun playing sports with your friends
walking around going to shops socializing sitting
in a bar drinking sleeping a lot of these things
are way more natural than staring
at an LED flickering screen uh where you're exposed to
you know rage bait online and things you know
and and all of that so he's absolutely right you know
that that yes even if it comes with you know a beer
in one hand it's actually way healthier than
than, you know, being a golem inside that never sees the light
and is just sitting behind a
computer. So, relatedly, this might be a very weird question,
so I apologize in advance,
but there was a recent study, it was talked about
in the New York Times, and it shows,
I'm going to read this to make sure I get it right.
One in four Gen Z adults say that they
have never had sex, and the number of young people
who haven't had sex in the past year has doubled
from 2020 to 2024, from 12% to 24%.
In your medical opinion, and this is going to sound
strange. To combat the loneliness epidemic,
to combat isolation, is it actually healthy for
young people to be engaging in romantic relationships
and having physical attractions
to one another? Yes, Shabbos.
I mean, it really is the most important thing that you can do.
Anytime there's an epidemiological study,
it shows that being in intimate relationships
confers more happiness.
Having children confers more meaning and purpose in your life.
And if you now have replaced intimate relations with others with
pornography or chatting with people online instead of the real deal,
you've shut yourself off from one of the core components
of human happiness, which are these intimate, loving relationships.
And I mean, so it's just a huge disaster what's going on.
Okay, so on another concerning note,
according to the American Enterprise Institute,
30 years ago, the majority of men, this is close to 60%,
they reported having at least six friends.
Today, the number has been cut in half. Only 25% have close friends.
15% of adult men in America have no friends at all.
That's a fivefold increase from 1990.
Amongst my generation, Gen Z, 30%.
30% of Gen Z men have zero friends at all. What is happening?
and i know we've alluded to the medical
and scientific problems with suicidality with
depression with anxiety but just from a friendship perspective
this is this is insane i mean i can
speak i'm a millennial
and i can kind of speak speak to how this has impacted me i i feel like
i've right now my whole life has been dominated
by work i mean that is the cultural values going
on and you know i often get up and leave
and i leave my friends behind and then i often find
myself socially isolated from others um i
also think you know the there's a lot of political
polarization going on right now there's a lot
of canceling going on online and i also think it kind
of scares people to open up and just be themselves
and that can create barriers but i'm gonna push
this back on you and you don't have to be an answer
but i'm just i'm just so curious i was
like what do you think is going on as you know someone down
in the the gen z trenches what do
you see happening? As the token Gen Z representative
for this conversation, I would say it's social
media. I mean, why do you need to have a physical relationship
when you have pornography in your
basement? I would say it's also a fear of cancel culture
and a blowback to me too. I'm scared of
asking that pretty girl out because I don't want
to have any type of professional blowback or social
isolation as a result. I do think to get a little political,
men have been stigmatized and told that
they are inherently due to their gender,
due to their race, are bad or racist or misogynistic.
And when you keep telling young people that thing,
they're actually going to believe you.
So I think the solution is not just medical or scientific.
It's also cultural and political.
I think, yeah, I mean, we're coming out of a period where
for the last 10 years we've been told, you know,
if you're if you're a man, especially if you're a white man,
you're privileged and you're kind of racist.
And you better watch out, buddy, because, you know,
if you say something that could even be perceived in a negative way,
you know, we're going to come after your job.
So you made this point that psychiatric medication does have potential
side effects. We know that this includes sexual dysfunction.
We know this includes emotional blunting.
We know that this includes dependence
and other long term complications. But I sort of want you
to preempt the nasty comments on YouTube who say, hang on a second,
are you really telling me that someone who is depressed
or someone who is anxious should not be on any medication at all?
Like, how do you know to draw the line between when someone needs
to just go on a walk, needs to solidify relationships versus,
no, this person really has a chemical imbalance.
We really do need to treat them with medication.
Yeah, we need to move back to a common
sense approach to using the drugs.
No drugs are bad.
I mean, they're essentially tools that you have in a toolkit to use.
But if you OK, so if if you come to me and you are saying,
hey, I'm depressed and I just put you on Prozac,
did I did I really help you if I don't understand your life?
Because let's say I dig a little deeper and I find out that you
walk 4,000 steps a day, that you don't move your body, that you,
you know, rarely get out of the house before 11 a.m. in the morning.
You kind of wake up and you flip open your laptop
and, you know, you go to work.
You know, you also drink several cups of coffee a day.
You're using nicotine products.
You drink a couple drinks to go to bed at night.
um and and and yes i could say well you know
technically you meet criteria for major depressive
disorder because you feel terrible
and you're eating bad food and put you on the prozac is that
really good medical care it's not that's crap i mean
that's you you wouldn't want anyone
to have that and that's pretty much what most people
in our country are getting today they are
getting care from uninvested doctors
who do not understand their lives because all of that stuff
getting that fixed, moving your body more,
cleaning up your diet, exercising, getting out
into nature early in the morning to set up
your circadian rhythm properly, spending time outside.
All of those things are the things
that actually make people feel better. And when we just paper
over them with drugs that don't address those problems,
they just fester and people get worse.
Now, if you come to me and you say, hey,
Dr. Yosef, I've done all those things. I'm super
invested in my healthcare. My relationships are good.
I've got meaning and purpose in my life.
and I'm healthy, I'm still feeling bad, I'll say, you know what?
Let's use some Lexapro. Let's use
some Prozac. You've done all the non-drug alternatives.
You've really tried to get to
the root cause. We can't find them.
Now let's treat this more like a genetic depression and
just, you know, we'll talk about the risks
and benefits and we'll use it in that way.
But that's like, that doesn't happen to anyone right now.
Like most people, you know, they just,
they come and say I'm depressed and they get a drug.
And so that's, that's my problem with the
current system. You know, Dr. Mitt, I shouldn't say this,
but the real reason we booked you is
I essentially wanted a free consultation because I'll just say that,
you know, post-October 7th,
I was diagnosed with anxiety.
I was diagnosed with depression and I was given medication,
a heavy dosage, I would say.
And I gained a tremendous amount of weight. It didn't really
make me feel better. And I would just add that anecdotally,
what you're saying really resonates
because what did in fact help was going on walks,
was making friends, was solidifying,
you know, previous relationships.
It was things like that. So obviously every individual is
different, but I very much relate to what you're saying.
But I do have to ask, when you talk about
these doctors who are over-prescribing
or they're treating an algorithm rather than a patient,
I mean, most individuals watching this would say,
well, you know, I know my doctor. My doctor,
for the most part, has my best interests at heart.
So where is this coming from? Is this
really because of the pharmaceutical companies?
Is this because of bad policies or politics?
Like, why are they doing this? These are not bad people.
Yeah, Shabbos, it's two things.
The first thing is the pharmaceutical industry. Now,
when it comes to antidepressants i mean
these these are some of the most successful drugs of
all time i mean they made Eli Lilly a billion dollar company
and they've done the same for
many others when you essentially have like five
or six different companies selling these drugs
you have billions of marketing spend
which are trying to control the narrative about these
medications and the most effective thing
that they ever did was convince the public that
that depression is a genetic problem it's medical in origin
and it needs to be treated by drugs
That is not true at all.
It is not backed up by the medical literature. And depression is much
more broad and should be addressed in more holistic ways.
So that's the first thing they
did. They convinced the public
and the doctors to look at depression in that way. The second
major player is simply an economic one.
Back in the 90s, health insurance companies conglomerated
and they negotiated with doctors on how much they
were going to get paid per visit. That number was
so low that doctors now have to see people
with seven minutes of face time to essentially make
the medical practices economically viable
and so you have these lovely people these are doctors in
our families these are our friends these are our parents
who essentially are trying to do a job
with a hand tied behind their back now if you're seeing
if you have to see like four or five people
an hour you have a patient panel
of 2,000 people how well can you understand their lives you can't
It's effectively impossible. And so these good people,
they do what they can in their limited time, which is essentially,
oh, you filled out this questionnaire, you're depressed,
and I know that there's an FDA-approved drug for this.
Let me just prescribe that.
And so that's essentially what's happening. These aren't bad people.
They just don't have the time to do the job properly.
Doctor, in the minute I have with you left, I want to talk about something
that is somewhat tangential to this conversation,
but actually incredibly important, especially with my generation.
And that's talking about someone I wish we weren't clavicular.
And just in general, the dangers of the looksmaxing movement,
including obviously, the rising use of stimulant drugs,
chief among them, Adderall.
We also know that clavicular himself overdosed and had a seizure
on livestream in front of 10s of millions of young Americans watching.
Can you just bring attention to this issue?
Why would you say that looks maxing from purely
scientific and medical reasons is such a dangerous trend?
I love this question,
Chavis. No one has ever asked me this before, and I'm so ready for it.
It's the greatest thing.
You got to talk to more young people, doctor.
Yeah, yeah. I have to. When I look at someone
unlike Clavicula, I just think about him being just
the product of social media and crap values.
If you turn on social media, it's all about how good looking are you?
How much money do you have?
It's a real flex culture.
And so you get these impressionable people who think,
oh, this is just what I have to be.
And I can't blame them for that. I mean, if that's what
the algorithm is feeding you,
and there's a lot of that stuff on the algorithm,
it can throw you into these really dark holes now here's why it's
a bad thing it's a bad thing
because that doesn't lead
to happiness over time you know how how good looking you are or how
wealthy you are i mean it's it's a cliche money doesn't buy happiness
and and all of that and so
if you spend five hours a day listening
to that stuff you're going to start developing body
dysmorphia and getting looks maxing
and getting all of these surgeries and things like that
but there's so much more to life than what you look like you know
for instance you know living
a life in service of others you know charity relationships you know
a lot of the great values
that we used to get from church and our elders
and a lot of that stuff is just now being washed
away because people don't go to church anymore
and it's being replaced by this garbage online
and that's why you get people like Klavikula
who are taking amphetamines to try and stay cut
and psychiatric drugs.
And he's going to have
a mental health crisis.
I mean, I don't want this for him,
but I would not be surprised
if we hear about
a mental health crisis
because he is living
in an incredibly unhealthy way,
physically and psychologically.
It's almost like a train wreck
that's about to happen.
Unfortunately, we got to end it there,
but this has been
a really fascinating,
albeit depressing,
yet nevertheless important conversation.
Dr. Joseph Witt,
during former FDA medical officer,
board-certified psychiatrist and, of course,
CEO and medical director of Tabor Clinic. Doctor,
very much appreciate you making this on.
Chavez, so great to talk with you about
Klavikula and all these things.
Well, thank you so much for watching this week's episode
of The Brief. Feel free to keep the conversation going
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