Joe Manganiello discusses memoir 'Bloodlines'

Fox - LA
12 followers
Oct 23, 2026
Welcome back. We always love having him here,
but this time Joe Manganiello is sharing a much
more personal side of himself.
The actor we know from True Blood and Magic Mike has a new book out
called Bloodlines, and it's about so much more than his Hollywood life.
Joe opens up about a
years-long health battle that nearly took his life,
the search for answers when medicine couldn't
explain everything and how that journey led him
to discover some extraordinary things about his
family's history it is a story about survival identity faith
and what we carry with us sometimes
without even knowing it it's
so nice to have you back with us nice to see you and the first
question obviously is how are you doing how's
your health right now great yeah someone backstage was
like are you all right i'm like yeah i slept great you know yeah
no i um no this this story
i mean the story documented in the book starts about 10 years ago
and um it's about this 10
year battle in secret with this host
of mystery illnesses.
Come to find out my grandmother, half German,
half Armenian baby born in a relocation camp
in the wake of the Armenian genocide suffered almost all
of the same conditions that I did.
So as I was going from doctor to doctor
and dermatologist to dermatologist and all of
my conditions were being split into different parts
and I'm being sent to different doctors
who want to put me on different drugs to solve them all
the underlying condition i realized was passed
down to me created by this you know
by by what we would consider generational trauma caused by the
genocide talk about what you went through
because this is really some scary stuff to the point where
you're being pumped up all this medication
is being pumped into your body at the same time
you're trying to be very private about it
because you're getting these opportunities that are big
deal in your career, right?
Major roles, right?
At the same exact time.
Yeah, but also, I'm afraid.
There are people who knew that I
was sick, that I had to be removed
from a set, and so there are
paparazzi all over my house.
There are paparazzi trying to
figure out what hospital I'm in,
what room I'm in, trying to get
the first pictures of me sick.
So that drove me into a corner
where I felt like I can't come out
with this, or I need to put out
a story to say that my appendix
was removed to try to get them off of me.
My appendix was removed, but along with lots
of other stuff too. My whole large intestine
was cut out early on and I lived with an ostomy
bag for a period of time and was concerned that it might be permanent.
And then that kind of kicked off this seven year up
and down battle where every time I
wanted to come clean, every time I wanted to live authentically,
something would happen
and get in the way of that and I would feel like I couldn't
do that in reading your book I actually
in listening to your book
because I did the audible you know it helps with the freeways here
in LA driving I got through it it was nice
because it felt like you were reading to me
um every time I was like oh okay it's gonna get
better it would keep getting worse yeah you know
my mother um couldn't acknowledge that I
was writing this book partially because her mother
my grandmother who passed
away out of complications with autoimmune
conditions, she was so traumatized
by losing her mother early that
it made it so that for the rest of her life
it was difficult to talk about. And then of course
her son heading into the same age
she lost her mother, starts getting sick.
It really pushed her
into a place where she couldn't deal with it.
So I sent her the audio
book and she started listening to it
and then she got to a place where she couldn't go any
further. So I came to her house and
sat with her and we got through the difficult parts
and my mother said does it ever get any
better of course like as if i wasn't sitting there
in front of her like yeah i'm right here
what really struck me though is that you're dealing
with this in private you just landed
this major motion picture role where you're doing you have
to be the best shape of your life
and he was the best shape right and do these scenes
but when i get offered i'm in the worst
shape of my life right exactly and yet you're trying to train
and and get fitted for armor for
this and you're trying to hide your condition.
And I think what's so relatable about
that is that so many people kind of live like that,
right?
They try to put on an armor and face the responsibilities
of their life, their work, their job, their
family and put on a strong face,
yet you're suffering inside and in private.
Yeah, I mean, you're trying to be strong for everybody around you.
I mean, especially as a man, that's what you do.
You don't make anybody else's life more difficult.
You make people's lives simpler.
You take care of people you provide for.
So when all of that starts being taken away
and you start being stripped down, your identity
goes into this, basically this whirlpool,
and so it was the book is a lot of me letting
go of the things that I thought I was.
It was this identity,
this life that I had created and spent so much hard work creating
for myself.
It's about what happens when you realize what you've inherited,
like the life you created
can't hold what you inherited
and you have to give in and you have to allow this thing
to happen.
And, you know, I really feel like the book
was the book was my purpose of the first half
of my life was to be here talking about this now.
And especially, as you know, for a lot of people,
the Armenian genocide didn't exist
or wasn't taught until they either heard me talk about it
on a show like this or
read about it in the book. And I find lots
of people that it's educational for them because
growing up as an Armenian, I didn't know who I was.
I didn't know what all of that meant because
you're a kid and they're not going to tell
a little kid what happened. And so really it's
about a discovery process of who I am and what I'm carrying.
And kind of like I feel like I'm
a representative for my ancestors. Absolutely.
When you did that episode of Finding My Roots,
And you know this, you've mentioned it also in your book,
all of a sudden, you got such
a big response.
Did you feel like you found your community in a way?
And how much it meant that someone like you
was just saying the words Armenian genocide?
Yeah, I had no idea.
I was just, people would say,
you're being political, no, I'm being personal.
This is a personal story to me
and I didn't know how much just merely telling my great
grandmother's story was going to mean to Armenians.
And people would say, I'm
so happy you discovered your Armenian roots, it's like, no, no, no.
My mother's more culturally Armenian than anything.
The food she cooked for me growing up, yeah,
it's my great grandmother and my grandmother.
But when I went, finally got to go to Armenia and saw the pomegranates,
pomegranate juice
on the sidewalk and lavash everywhere, sujuk and eggs,
I mean, I ate sujuk and
eggs for breakfast.
Like every weekend that I was home from college,
I would come home, my mother knew what I wanted
to eat.
What a full circle moment for you to take that trip,
I think, to Armenia, which obviously,
at the end of the book, you make that full circle connection.
But you took this trip to Armenia.
You went with the organization,
Children of Armenia Fund, which both you and I, every
December we meet in New York, it's become our tradition.
Talk a little bit about what that experience was like.
There we see bubbles along with your fiance, Caitlin O'Connor.
Yeah, and they're making lavash.
Yeah, and then I visited all of the monasteries
and the framework for the book, I didn't know
where I was gonna land the story or where it was gonna end.
But the book is split into three acts
and the first act I named the flood, because it
felt like this illness started, it was like the rain was starting.
And then this flood washed away what I thought
my life was supposed to be.
Now by the end of act three,
I wind up in Armenia in the shadow of Mount Ararat, which
everybody knows is where we believe Noah's Ark landed
and life started over.
So it was about letting go of what I thought
my life was supposed to be and accepting that
this was my journey, and that it's gonna be okay.
A lot of symbolism.
And so many levels here in this story of your personal story,
but internally, externally,
physically, what does healing mean to you?
Because healing was not just physically for you,
there's so many levels here.
talk about your deep cultural past.
Yeah, I really feel like I was handed a bar
tab for a bunch of food and drinks that I did not order.
And the people who ordered
it were gone. And life wasn't gonna let me leave until somebody paid
for it. And I really
feel like in going through this journey
and connecting these dots the way that I was able
to in the book i i not only healed myself
but i feel like i healed my ancestors that that that
their lives weren't in vain that i get
to talk about them say their names talk about the struggles
that they went through
and i feel like that there's this i don't know this calm that has
happened you have made me cry you have
a very calm presence um uh tell people how you healed
though, as far as you're healthy now. How did it just end?
Well, I wound up talking to Dr. Gabor Maté.
And Gabor Maté is a Hungarian Jewish
doctor whose family survived the Holocaust, the Jewish Holocaust.
And there's a lot of
Jewish people that suffer from the same conditions that,
these autoimmune conditions that I find
that I suffer from.
I meet a lot of Armenians that do, I meet a lot of Greeks that do. But
But it's not only specific to that area.
I have friends of mine who are Vietnamese,
and they talk about the trauma of their mother
was pregnant, they're on a raft,
they think the pirates are gonna take the baby away.
This is not unique to any one culture,
but I really feel like it was an unraveling and
untying of those knots that were passed down.
The generations prior didn't talk.
Yeah, that's true.
And then you, as a descendant,
get handed these things that they don't talk about.
And when you do start talking,
whether you're artists or black sheep in the family, like,
Why don't you shut up and stop talking about us all, please?
Right, don't talk about our family secrets.
Please talk about anything, but we have to.
And I guess the message here is whether you're suffering
with an ostomy bag, you're suffering,
you've been passed down some mystery illness,
whatever it is, it's important to talk about
that.
that down and repress that because that's what makes you sicker.
I do want to give Bubbles some acknowledgement here
because people have seen Bubbles with you.
And it's been strange for people
who don't know the significance of Bubbles and how Bubbles came
into your life because you're this big guy
and there's this little tiny dog. But Bubbles really
helped you heal. And I think you needed Bubbles
as much as Bubbles needed you.
100%. Yeah, Bubbles is the subject of chapter three in the book.
She came to me at one of the
darkest moments during the illness where I
was having trouble finding the strength to want to
wake up in the morning. I didn't want to wake up anymore.
And here comes this little dog who
was sick in some of the same ways that I was.
She was bleeding. I was bleeding. I just saw this
little thing that needed these surgeries
and was in danger of being put down because the shelter
didn't have the money to pay for these surgeries.
And I've never had a pet in my life. Never wanted
a pet, I'm not, but she chose me and it was almost like she was saying,
please help me
and then I'll help you.
And so I took her, I got her the surgeries
and then she would lay on my, where the surgeries
were on me, she would come and lay on them.
When I didn't wanna eat, because eating
for me got really painful and I started losing
weight, she would make sure that I would go and eat,
and I think she wanted snacks, but
she would make sure, you have to do this, you have to do this.
When I was in pain and laying on my side,
she would come take me outside, take me outside.
She knew when I needed to walk, when I needed to eat,
she could tell when I was having trouble.
So I nursed this little thing back
and then she walks me back into life, yeah.
So I take her everywhere.
But sometimes guys are like, hey,
what's up man, what's up with the little dog?
You're a tough guy, come on, what's with that image?
What happens when I put the dog down?
I'm like, no, no, no, let's not do this,
let's not do, I try to be, no, no, no.
You know how it is.
I mentioned your fiancee, Caitlin and Connor.
What is something that going through
this experience taught you about love and relationships?
Well, very early on, I wanted to be honest with Caitlin.
And I was scared about being accepted
if I opened up to somebody about my illness.
I was a complicated person at that point.
And on our second date, I told her the truth
about what had happened to me because I didn't
want her to feel like I tricked
her or baited her into being with somebody.
And so that kind of love and acceptance,
it made me understand that I didn't have to feel
the kind of shame or guilt of having this illness
and having been through that,
that there was somebody who would love me for it unconditionally.
Well, I mean, we just started talking about this.
There's so much more to talk about, which leads me to this.
Bloodlines now available where you can pick up books,
but also Sunday, Joe will be signing his book
at the Americana at Brandon Glendale.
And before the signing, I will sit down with Joe again,
and we'll continue this conversation.
You can get tickets to this event at eventbrite.com.
Thank you so much for coming in.
We're so glad you're doing well and really appreciate it.
And thank you for agreeing to come out
to talk to me in Glendale on Sunday.
Maybe we'll go to the carousel afterwards, right? Okay.
