0:00 Welcome to psychology for sleep 2:01 The paradox of tired wired syndrome 6:50 The exhaustion arousal cycle and neurochemical confusion 12:06 Default mode network disruption and intrusive thoughts 18:26 Circadian rhythm misalignment and the sleep pressure paradox 24:02 Amygdala hyperreactivity and the emotional vulnerability of exhaustion 31:09 Muscle tension, temperature regulation, and the reticular activating system 38:12 The brain's blood flow patterns and thalamic filtering failure 47:11 Interoception, sleep-onset dreams, and the locus coeruleus paradox 53:27 Glucose metabolism, orexin, and the metabolic trap of sleep initiation 58:57 Micro-arousals, parasympathetic failure, and the self-reinforcing cycle 1:04:50 Cortisol, melatonin, GABA, and histamine: the chemical contradictions 1:11:26 Serotonin, dopamine, adenosine receptors, and inflammatory cytokines 1:13:48 Neuropeptide Y, acetylcholine, and the loss of orchestrated timing 1:16:49 Endorphins, oxytocin, galanin, and the systems-level desynchronization 1:20:54 Contextual conditioning and the bedroom as a site of vigilance 1:24:02 Sleep effort as a self-perpetuating problem 1:27:58 Cognitive fusion and the identity of sleeplessness 1:31:09 The physiology of catastrophic thinking about sleep 1:34:59 Hyperarousal and the self-perpetuating cycle of exhaustion 1:38:12 Emotional regulation and attentional control in exhausted wakefulness 1:42:55 Social cognition and isolation in chronic sleeplessness 1:47:11 The complex systems failure of exhausted wakefulness 1:50:41 Somatic patterns and the body's role in maintaining arousal 1:53:27 Chronotype mismatch and the impact of circadian disruption 1:58:57 The role of dreams, nervous system regulation, and meaning-making
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