Effect of Hormone Imbalances on Energy, Sleep, Depression & AnxietyEffect of Hormone Imbalances on E

Integrative Behavioral Health and Neuropsychology (CEUs Available)
#lowt #menopause #hormoneimbalances #insomnia
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– Estradiol is predominant prior to menopause
– Estrone is the primary form postmenopausally
– Synthesized by fatty tissue
– Estrogen works synergistically with many biological systems to promote physical, cognitive and affective function
– Estrogens can modulate neuronal excitability, through serotonin, norepinephrine, dopamine, and endorphin regulation
– Estrogen supplementation can decrease both systolic and diastolic blood pressures and reduced norepinephrine levels

Estrogen
– Estrogen modulates mood via the serotonergic system
Estrogen
– Estrogen also regulates glucose metabolism and energy production
– Declines in these processes are characteristic of neurodegenerative diseases
– Estrogens exert neuroprotective actions to maintain cerebrovasculature health including prevention glutamate-induced excitotoxicity and hippocampal shrinkage
– Estrogens exert some anti-inflammatory effects
– Naturally occurring higher levels of estrone were associated with poorer cognition, specifically working memory performance
– Estradiol acts in part through nitric oxide (arginine)to increase extracellular dopamine levels.
– Premenopausal females have a better response than males to serotonergic antidepressants