Collodion Baby Causes, Risk Factors, Complications, & Treatment

Collodion baby, also known as lamellar ichthyosis, is an autosomal recessive disorder, where the newborns are born with a collodion membrane, enclosing the whole body, as you can see in this picture.
The membrane sheds within 10 to 14 days, revealing generalized scaling with variable redness of the skin.
The scaling may be fine or platelike, resembling fish skin.
Although the condition is not life threatening, it persists throughout life, causing significant psychological stress to affected parents.
Consanguinity has been identified as a main risk factor for lamellar ichthyosis.
Patients with lamellar ichthyosis have a normal life expectancy.
However, scaling of the skin may lead to obstruction of sweat glands, causing problems in temperature regulation.
In addition, they are at a high risk of dehydration.
Secondary bacterial infections are also common among the affected patients, especially ear infections.
Nail dystrophy, ectropion formation, and scarring alopecia are some other complications of lamellar ichthyosis.
Skin moisturizers are the first line agents in the management of lamellar ichthyosis.
They serve as a barrier and are helpful to remove scales.
For neonates, electrolytes should be monitored closely.
Oral retinoids are effective to overcome heat intolerance.
Finally, artificial tears and eye lubricants are indicated for patients with ectropion.

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