A 12-week, triple-blind study reports that a standardized chamomile extract reduced a range of menopausal symptoms in postmenopausal women, with some participants experiencing side effects.
By yourNEWS Media Newsroom
A controlled clinical trial has found that chamomile extract may provide measurable relief for several common menopause-related symptoms, according to research published in the journal Menopause in January 2025.
The study followed 80 postmenopausal women between the ages of 47 and 62 over a 12-week period. Participants who received chamomile extract reported improvements in hot flashes, night sweats, mood fluctuations, joint and muscle discomfort, and urinary symptoms when compared to those given a placebo.
Researchers used a triple-blind design, meaning that participants, administering clinicians, and data analysts were all unaware of who received the treatment or placebo. This structure is intended to minimize bias and strengthen the reliability of the findings.
Women in the treatment group were given capsules containing 100 milligrams of chamomile extract standardized to 1.2% apigenin, taken four times daily. Apigenin, a naturally occurring flavonoid found in chamomile, is known to interact with GABA receptors in the brain, which are involved in regulating mood, sleep, and nervous system activity.
The results showed statistically significant improvements across all major symptom categories measured using the Australian Menopause Association’s Scorecard Symptom Questionnaire. Overall symptom scores declined by more than 10 points in the chamomile group relative to the placebo group.
The study documented reductions in vasomotor symptoms such as hot flashes and night sweats, as well as improvements in psychological symptoms including anxiety, irritability, and mood swings. Participants also reported relief from joint stiffness and muscle pain, along with fewer urinary-related complaints.
Two participants in the chamomile group withdrew from the trial due to side effects, including mouth sores, skin spots, and itching. While such reactions were not widespread, researchers noted that they highlight the need for caution when using plant-based supplements.
Chamomile, specifically Matricaria chamomilla, has long been used in traditional settings for its calming properties. However, the concentrated extract used in the study delivered higher levels of active compounds than would typically be consumed through tea.
Researchers noted that individuals with sensitivities to plants in the Asteraceae family, including ragweed and chrysanthemums, may be at higher risk of allergic reactions. They also advised that individuals with hormone-sensitive conditions or those taking certain medications consult healthcare providers before using chamomile supplements.
The findings come amid continued interest in non-hormonal approaches to managing menopause symptoms. While hormone therapy remains a treatment option for some, the study highlights an alternative that may appeal to individuals seeking plant-based interventions.
Researchers emphasized that chamomile is not a substitute for medical treatments in severe cases but may offer a supportive option for managing mild to moderate symptoms.
Source: Natural News
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