By Elsie Kamsiyochi

The United States and Iran are preparing to enter a new round of high-stakes peace negotiations in Islamabad, mediated by Pakistan, yet both governments are approaching the talks with hardened positions and limited trust. Despite U.S. President Donald Trump’s remarks that Tehran’s latest proposals could serve as a “basis” for discussion, the two sides remain deeply divided on the most sensitive issues shaping the region’s future.

The meetings come at a moment of profound tension. Inside Iran, public emotions are still raw following ceremonies marking 40 days since the death of Ayatollah Ali Khamenei, who was killed in joint Israeli–U.S. strikes. Across the Middle East, violence continues in multiple theatres, and the consequences of the war are still unfolding—from Lebanon’s devastation to the unprecedented disruption of global energy markets. Against this volatile backdrop, the question is whether Washington and Tehran can actually craft a settlement durable enough to alter the strategic landscape for years to come.

WHERE DO BOTH SIDES STAND?

An Iranian delegation is expected to arrive in Islamabad with a 10-point framework that differs significantly from Washington’s earlier 15-point plan. The lack of overlap highlights how vast the distance between the two governments remains.

Tehran’s blueprint demands the right to enrich uranium—an issue the U.S. has repeatedly declared non-negotiable, with Trump insisting enrichment is off the table entirely. The Iranian plan also sidesteps any restrictions on ballistic missiles, even though the U.S. and Israel view missile limitations as critical to any final agreement.

Iranian leaders argue that the missile program is essential for national security and deterrence, and officials have implied that no meaningful compromise is possible. Yet analysts remain uncertain about how much of Iran’s arsenal survived the war, a factor that could influence Iran’s negotiating leverage.

According to a Pakistani official familiar with the mediation efforts, Iran may succeed in securing major concessions linked to reconstruction, sanctions relief, and reparations. However, the official stressed that uranium enrichment is almost certainly a “red line” that Washington will not cross.

WHAT WILL TOP THE AGENDA OF THE ISLAMABAD TALKS?

While nuclear and missile issues have shaped past negotiations, today the most urgent topic is the fate of the Strait of Hormuz—one of the world’s most vital energy chokepoints. Since February 28, Iran’s effective closure of the strait has triggered the most severe disruption to global oil and gas shipments in recorded history, sending prices sharply upward and raising fears of a long-term global economic shock.

Tehran has signaled that under any enduring peace agreement, it would expect to impose a transit fee on ships moving through the narrow passage, which at its slimmest span is only 34 kilometers wide. The U.S., meanwhile, has demanded that Iran immediately reopen the waterway, with Trump previously threatening “devastating” consequences if Iran refused.

Despite the U.S. pressure, there is still no indication that Iran has lifted the blockade. Tehran insists it will not fully engage in a ceasefire or maritime reopening so long as Israel continues its operations in Lebanon—a conflict Iran views as inseparable from its own security.

HOW DO IRAN’S 10-POINT AND U.S. 15-POINT PLANS COMPARE?

Iran’s Supreme National Security Council announced that Washington had “in principle” agreed to core components of its proposal—claims the U.S. has not publicly confirmed. Tehran said the U.S. had accepted non-aggression guarantees, recognition of Iran’s authority over the Strait of Hormuz, permission for uranium enrichment, removal of all sanctions, annulment of U.N. Security Council and IAEA resolutions, withdrawal of American forces from the region, and a complete halt to regional hostilities, including the war in Lebanon.

Israeli officials, however, point to a very different American offer previously transmitted via Pakistan. Trump’s 15-point plan demanded the elimination of Iran’s enriched uranium stockpile, a total halt to enrichment, severe limits on ballistic missiles, and an end to Iranian financing of allied militias and political movements across the Middle East.

Trump has warned that U.S. military forces will remain in the region until a final peace deal is secured and has threatened dramatic escalation if Iran does not comply.

WHAT ARE THE CHANCES OF REACHING A LASTING SETTLEMENT?

Although Trump has claimed victory in the conflict, Washington has not yet achieved the sweeping goals it set at the war’s outset—neutralizing Iran’s capacity to strike neighbors, dismantling its nuclear program, and setting the political conditions for Iranians to potentially topple their government.

Iranian officials appear confident they can continue the fight indefinitely if required. With control over the Strait of Hormuz offering unprecedented economic leverage, Tehran believes time may be on its side, even in the face of U.S. military superiority.

This dynamic—military might on one side, strategic endurance on the other—complicates the path to any sustainable peace.

WHAT IS ISRAEL’S POSITION AND WHERE DOES LEBANON FIT IN?

Israel views Iran as an existential threat and continues to wage a separate but intertwined conflict against Hezbollah in Lebanon. Prime Minister Benjamin Netanyahu has long favored regime change in Tehran, even though such an objective would likely require a costly ground operation with no guarantee of regional stability afterward.

The inclusion—or exclusion—of Lebanon has become one of the most contentious obstacles in the ceasefire negotiations. The U.S. and Israel insist that the Lebanon front is not covered by the ceasefire framework. Iran’s President Masoud Pezeshkian counters that halting attacks in Lebanon is an essential condition for any broader deal with Washington.

Israel has acknowledged agreeing to a ceasefire with Iran but maintains that it does not extend to its campaign in Lebanon, raising doubts about whether a lasting regional truce is feasible.

Original article