NEONATAL seizures! Work-up and TREATMENT!!
NEONATAL seizures are common! Do we ALWAYS treat them? What are the (million!) diseases that can cause seizures in babies? What is EPILEPSY? How do we work-up the cause for the seizure? Where do we start!!?? Do we always need a spinal tap? How do we manage seizures? What about imaging? What medications do we use? When do we STOP meds? What is the prognosis of an infant with seizures?
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Dr. Tala is a board-certified neonatologist and has worked in busy level III and IV units for the past 17 years. She has won multiple teaching awards throughout her time as a neonatologist.
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References:
Thumbnail from this website: https://www.childneurologyfoundation.org/disorder/infantile-spasms/
https://drdina.ca
Epilepsia, Volume: 62, Issue: 3, Pages: 615-628, First published: 01 February 2021, DOI: (10.1111/epi.16815)
Pressler RM, Cilio MR, Mizrahi EM, Moshé SL, Nunes ML, Plouin P, Vanhatalo S, Yozawitz E, de Vries LS, Puthenveettil Vinayan K, Triki CC, Wilmshurst JM, Yamamoto H, Zuberi SM. The ILAE classification of seizures and the epilepsies: Modification for seizures in the neonate. Position paper by the ILAE Task Force on Neonatal Seizures. Epilepsia. 2021 Mar;62(3):615-628. doi: 10.1111/epi.16815. Epub 2021 Feb 1. PMID: 33522601.
Huang LT, Tain YL, Lai MC, Yang SN. Neonatal seizures: dialogues between clinic and bench. J Formos Med Assoc. 2012 May;111(5):239-44. doi: 10.1016/j.jfma.2011.12.007. Epub 2012 Apr 7. PMID: 22656393.
Mosca S, Martins J, Temudo T. Transient benign paroxysmal movement disorders in infancy. Rev Neurol. 2022 Feb 16;74(4):135-140. English, Spanish. doi: 10.33588/rn.7404.2021326. PMID: 35148422; PMCID: PMC11502177.
Sandoval Karamian AG, DiGiovine MP, Massey SL. Neonatal Seizures. Pediatr Rev. 2024 Jul 1;45(7):381-393. doi: 10.1542/pir.2023-006016. PMID: 38945992.
Santarone ME, Pietrafusa N, Fusco L. Neonatal seizures: When semiology points to etiology. Seizure. 2020 Aug;80:161-165. doi: 10.1016/j.seizure.2020.06.025. Epub 2020 Jun 18. PMID: 32585613.
Epilepsia, Volume: 62, Issue: 3, Pages: 615-628, First published: 01 February 2021, DOI: (10.1111/epi.16815)
Malone A, Ryan CA, Fitzgerald A, Burgoyne L, Connolly S, Boylan GB. Interobserver agreement in neonatal seizure identification. Epilepsia. 2009 Sep;50(9):2097-101. doi: 10.1111/j.1528-1167.2009.02132.x. Epub 2009 Jun 1. PMID: 19490044.
Geneviève Malfilâtre, Luc Mony, Danièle Hasaerts, Patricia Vignolo-Diard, Marie-Dominique Lamblin, Emilie Bourel-Ponchel,
Technical recommendations and interpretation guidelines for electroencephalography for premature and full-term newborns,
Neurophysiologie Clinique, Volume 51, Issue 1, 2021,
Pages 35-60,ISSN 0987-7053,
https://doi.org/10.1016/j.neucli.2020.10.005.
Puthenveettil, Vinayan & Moshe, Solomon. (2014). Neonatal seizures and epilepsies. International Journal of Epilepsy. 1. 10.1016/j.ijep.2014.08.001.
Summarization of neonatal video EEG for seizure and artifact detection - Scientific Figure on ResearchGate. Available from: https://www.researchgate.net/figure/A-Typical-Setup-of-Video-EEG-System_fig2_279851141 [
Yozawitz E. Neonatal Seizures. N Engl J Med. 2023 May 4;388(18):1692-1700. doi: 10.1056/NEJMra2300188. PMID: 37133587.
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***TIMESTAMPS***
00:00 Intro
00:42 What causes seizures?
07:20 Work-up of seizures?
23:55 Manage and treat seizures?
31:!5 Prognosis after seizures
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*Disclaimer*: This video is intended for educational purposes only and while we strive to give the most accurate information, errors may occur. Subsequently, this video should not be a replacement for medical advice.